Scientists discover fungi has untapped potential to produce new antibiotics and ask for governments help to realise it

Scientists have discovered the potential for new antibiotics by locating the genes responsible for the production of various bioactive compounds, like antibiotics, in 24 different kinds of fungi.

Now they have asked for governments help to turn their discoveries into drugs that can help people.

Using fungi as a source of new antibiotics was discovered by researchers at Chalmers University of Technology who found that fungi produce many more natural and bioactive chemicals than was previously thought.

“We found that the fungi have enormous, previously untapped, potential for the production of new antibiotics and other bioactive compounds, such as cancer medicines,” said Jens Christian Nielsen, a PhD student at the Department of Biology and Biological Engineering.

Image courtesy of Jens Christian Nielsen

Having discovered their potential, the scientists are now calling on governments to support clinical trials that would help kick-start production.

When antibiotics are used, they are typically used with the short-term in mind, in contrast to the long-term therapies that help bring in revenues for pharmaceutical companies.

However, the dangers posed by antibiotic resistance, where simple infections could become lethal once again, means the need for new antibiotics is now urgent.

“Governments need to act. The pharmaceutical industry doesn’t want to spend money on new antibiotics, it’s not lucrative. This is why our governments have to step in and, for instance, support clinical studies. Their support would make it easier to reach the market, especially for smaller companies. This could fuel production,” said Christian Nielsen.

“It’s important to find new antibiotics in order to give physicians a broad palette of antibiotics, existing ones as well as new ones, to use in treatment. This will make it harder for bacteria to develop resistance.”

Image courtesy of Jens Christian Nielsen

The idea to study Fungi was inspired by the fact that the first antibiotic to be mass-produced –penicillin – was derived from Penicillium fungi.

But while previous efforts to find new antibiotics have mainly focused on bacteria, fungi remain an untapped resource.

“Fungi have been hard to study – we know very little of what they can do – but we do know that they develop bioactive substances naturally, as a way to protect themselves and survive in a competitive environment. This made it logical to apply our research tools to fungi,” said Christian Nielsen.

Valve’s ‘Knuckles’ controller brings individual finger control to VR

With a prototype first revealed at the company’s Steam Dev Days conference last October, Valve’s new ‘Knuckles’ controller is now being shipped to developers as a prototype, while a blog post unveils a few more of the specs.

What’s important about the new controller is that it on only utilises an ‘open hand’ design that will mean you don’t have to spend your entire time gripping the controller like a weapon, but  it also features basic tracking for individual fingers.

The device is similar to the current HTC Vive motion controller, positioning in 3D space via Steam’s Lighthouse tracking system, but looks to build to the next stage of what can be done with motion control in VR. Specifically, Valve is looking to bring a much greater presence of your virtual hand into the market.

Moreover, they’re looking to make that virtual hand feel far more natural. With the controller able to grip onto your hand – think somewhat similar to securing your Wiimotes to your wrist – you’ll be able to operate in the virtual space with an open hand. While it may seem a small thing, it brings a whole new realism to any kind of grabbing or catching motion.

In addition, the ability of the Knuckles to track the movement of individual fingers could prove a real game-changer to virtual reality experiences.  Using a number of capacitive sensors to detect the state of your hands when your finger is on a button, or particular part of a controller, the controller will, according to the dev post, “return a curl value between zero and one, where zero indicates that the finger is pointing straight out and one indicates that the finger is fully curled around the controller”.

In essence, this means that the controller will be able to sense fine gradations of movement in each of your fingers, rather than relying on a binary “open” or “closed” status. Beyond lending a more organic feel to the use of your virtual hand, this will also allow users to make use of a range of hand gestures currently unavailable with VR controllers. A screenshot from a new version of SteamVR Home displays the possibilities with a Knuckles user’s avatar throwing up devil horns.

Images courtesy of Valve

It’s worth noting that this isn’t a perfect tracking system. While farther along than, for example, the Oculus Touch controllers, which allow you to slightly open your fingers while tracking the three non-index fingers together via an analog trigger, the Knuckles aren’t exactly ‘full’ finger tracking. Ideally, controllers will reach the point of knowing where your fingers are at all times with pinpoint precision. Until then however, the Knuckles are no small step forward.

The current Knuckles controller dev kit reportedly has a battery life of three hours and requires an hour of USB Micro charging to fill up (if accurate, these numbers put it roughly in the same realm as Vive controllers in regards to battery). We’ll have to wait on confirmation of this and other details,

Elon Musk speaks to LA's mayor about his Boring Company

Elon Musk said this week that he has held “promising conversations” with L.A. Mayor Eric Garcetti, regarding the potential of bringing his recently formed Boring Company to the city. One of the ideas reportedly under consideration would see an express line to LAX airport from LA’s Union Station being built.

Source: Tech Crunch

Atari is back with a new console

Last week, Atari began teasing a new product called the Ataribox. Now, in an exclusive interview with GamesBeat Atari CEO Fred Chesnais has confirmed that the pioneering video game company is working on a new game console. “We’re back in the hardware business,” said Chesnais.

Source: Venture Beat

Nasa find 10 planets that could potentially host life

Nasa has added a further 219 candidates to the list of planets beyond our solar system, 10 of which may be about the same size and temperature as Earth, and may host life. Scientists found the candidates in a final batch of Nasa’s Kepler Space Telescope observations of 200,000 sample stars in the constellation Cygnus.

Source: The Guardian

Tesla Model S told driver to put his hands on the wheel before fatal crash

Federal regulators said on Monday, the driver of a Tesla Model S, who was killed in a collision while the car was in autopilot mode, did not have his hands on the steering wheel for a prolonged period of time despite being repeatedly warned by the vehicle that having his hands on the wheel was necessary.

Source: Ars Technica

Uber founder Travis Kalanick resigns

Having last week said that he was taking an indefinite leave of absence, Uber boss Travis Kalanick resigned as chief executive of the company this week after pressure from shareholders. His resignation comes after a review of practices at the firm and scandals including complaints of sexual harassment.

Source: BBC

Facebook defends against injunction to remove Oculus Rift from sale

Facebook and Oculus want a federal judge to let them continue selling Rifts despite a jury deciding Oculus stole another company’s computer code. Lawyers for Facebook said halting the sale of Oculus Rifts “would serve no one but ZeniMax, who would use it only as leverage to try to extract money from Oculus”.

Source: Bloomberg