Scientists develop lab-grown bone using tech originally used to detect gravitational waves

Scientists have described how technology originally developed to detect gravitational waves can be used to generate lab-grown bone.

Universities of Glasgow, Strathclyde, the West of Scotland and Galway scientists have developed the technique known as nanokicking, which allows scientists to grow three-dimensional samples of mineralised bone in the laboratory for the first time.

The technique could eventually be used to repair or replace damaged sections of bone in humans.

“This is an exciting step forward for nanokicking, and it takes us one step further towards making the technique available for use in medical therapies,” said Matthew Dalby, professor of cell engineering at the University of Glasgow.

“Now that we have advanced the process to the point where it’s readily reproducible and affordable, we will begin our first human trials around three years from now in the NHS along with the Scottish National Blood Transfusion Service and reconstructive and orthopaedic surgeons in Glasgow.”

Although bone is the second most grafted tissue after blood and is used in reconstructive, orthopaedic and cosmetic surgeries, currently surgeons can only harvest limited amounts of living bone from the patient for use in a graft, and bone from other donors is likely to be rejected by the body.

Instead, at the minute, surgeons have to rely on inferior donor sources that contain no cells capable of regenerating bone, which limits the size of repairs they can affect.

“For many people who have lost legs in landmine accidents, the difference between being confined to a wheelchair and being able to use a prosthesis could be only a few centimetres of bone,” said professor of bioengineering at the University of Glasgow Manuel Salmeron-Sanchez.

However, the process of nanokicking subjects cells to ultra-precise, nanoscale vibrations while they are suspended inside collagen gels.

The cells in the gels are the turned into a ‘bone putty’ that has the potential to be used to heal bone fractures and fill bone where there is a gap.

Using patients’ own mesenchymal cells, which are naturally produced by the human body in bone marrow, surgeons will be able to prevent the problem of rejection, and can bridge larger gaps in bone.

Before beginning human trials, the nanokicking technique developed by the researchers is currently being further tested in a network of laboratories across the UK.

“We have already proven the effectiveness of our scaffolds in veterinary medicine, by helping to grow new bone to save the leg of a dog who would otherwise have had to have it amputated,” said Dalby.

“Combining bone putty and mechanically strong scaffolds will allow us to address large bone deficits in humans in the future.”

The scientists work has been funded by Sir Bobby Charlton’s landmine charity Find a Better Way, which help individuals and communities heal from the devastating impact of landmines and other explosive remnants of war, and is published in Nature Biomedical Engineering.

Crypto-currency mining is hindering the search for alien life

Researchers searching for extraterrestrial life are struggling to get the computer hardware they need, due to crypto-currency mining. "We'd like to use the latest GPUs...and we can't get 'em," said Dan Werthimer. Demand for GPUs has soared recently thanks to crypto-currency mining.

Source: BBC

Genetic study of soil reveals new family of antibiotics

Researchers have discovered a new family of antibiotics in samples of soil. In their paper, published in the journal Nature Microbiology, the group describe how the antibiotics, named malacidins, have been shown to kill superbugs such as MRSA, which are resistant to current antibiotics.

Source: Phys.org

UK police are identifying suspects using fingerprint scanners

UK police have begun using a mobile fingerprinting system to identify people in less than a minute. Fingerprints are compared against 12 million records stored in the national criminal and immigration fingerprint databases and, if a match is found, return info like the individual’s name and date of birth.

Source: Wired

Robots 1,000 times smaller than a human hair could treat cancer

Scientists from Arizona State University and The Chinese Academy of Sciences just figured out how to build tiny robots that travel through the body's blood stream, hunting for tumors, without doing any harm to healthy cells along the way. In tests on mice, average survival times doubled.

NASA is bringing back Cold War-era rockets to get to Mars

NASA is planning to use atomic rockets to help get humans to Mars. Unlike conventional rockets that burn fuel to create thrust, the atomic system uses the reactor to heat a propellant like liquid hydrogen, which then expands through a nozzle to power the craft, doubling the efficiency at which the rocket uses fuel.

Source: Bloomberg

Facial recognition systems have gender and racial biases

Research conducted by Massachusetts Institute of Technology and Stamford University has found that AI-powered facial recognition systems have gender and racial biases, which means because they have been trained using large data sets of white males they are better at picking out that group than any other.

Source: The Inquirer

Skydio unveils its obstacle-dodging, thrill-seeking, AI-powered drone

An autonomous drone startup founded by former MIT researchers has today launched its R1, a fully autonomous flying camera that follows its subjects through dense and challenging environments.

In a promotional video, launched to introduce the autonomous camera, R1 can be seen following an athlete as she parkours her way through dense woodland.

The drone’s makers Skydio have explained that the camera combines artificial intelligence, computer vision, and advanced robotics and works by anticipating how people move, so R1 can make intelligent decisions about how to get the smoothest, most cinematic footage in real-time.

“The promise of the self-flying camera has captured people’s imaginations, but today’s drones still need to be flown manually for them to be useful,” said Adam Bry, CEO and co-founder of Skydio.

“We’ve spent the last four years solving the hard problems in robotics and AI necessary to make fully autonomous flight possible. We’re incredibly excited about the creative possibilities with R1, and we also believe that this technology will enable many of the most valuable drone applications for consumers and businesses over the coming years.”

Launching today is the Frontier Edition of R1, which is aimed at athletes, adventurers, and creators.

This version of R1 is powered by the Skydio Autonomy Engine, enabling it to see and understand the world around it so that it can fly safely at speeds of upto 25mph while avoiding obstacles.

The autonomous drone is fitted with 13 cameras, which gives it the ability to map and understand the world in real-time, allowing it to be fully autonomous and independently capture footage that in Skydio’s words “once required a Hollywood film crew” and will “enable a new type of visual storytelling”.

The R1 “Frontier Edition” is available for order now on Skydio’s website for $2,499.